12 Key Symptoms of Low Testosterone in Men Over 40

  • Written by Menova Health
  • Published 2025-09-04

As men age, testosterone levels naturally decline by approximately 1-2% per year after age 30. For men over 40, this decline can become more noticeable, affecting everything from energy levels to sexual health. Understanding the signs and symptoms of low testosterone is crucial for maintaining optimal health and quality of life.

Understanding Low Testosterone: What Every Man Should Know

Low testosterone, medically known as hypogonadism, affects nearly 40% of men over 45 years old. Whilst it's a natural part of ageing, the symptoms don't have to be accepted as inevitable. Modern hormone restoration therapy can help men reclaim their vitality and improve their overall wellbeing.

Normal testosterone levels typically range from 300-1000 ng/dL, with levels below 300 ng/dL generally considered low.

12 Key Symptoms of Low Testosterone in Men Over 40

Physical Symptoms

1. Decreased Energy and Fatigue Persistent tiredness despite adequate sleep is often the first sign men notice. This isn't just feeling tired after a long day – it's a deep, persistent fatigue that affects daily activities.

2. Reduced Muscle Mass and Strength Testosterone plays a crucial role in maintaining muscle mass. Men may notice their workouts becoming less effective or muscle definition decreasing despite consistent exercise.

3. Increased Body Fat Particularly around the midsection, low testosterone can lead to increased fat storage and difficulty losing weight, even with proper diet and exercise.

4. Hair Loss Whilst genetics play a role, low testosterone can accelerate male pattern baldness and reduce body hair growth.

Sexual Health Symptoms

5. Decreased Libido A noticeable reduction in sexual desire is one of the most common and concerning symptoms for men experiencing low testosterone.

6. Erectile Dysfunction Whilst ED can have multiple causes, low testosterone is a significant contributing factor, especially when combined with other symptoms.

7. Reduced Sperm Production Testosterone is essential for healthy sperm production, and low levels can affect fertility.

Mental and Emotional Symptoms

8. Mood Changes and Irritability Men may experience increased irritability, mood swings, or feelings of depression that seem uncharacteristic.

9. Difficulty Concentrating Often described as "brain fog," low testosterone can affect cognitive function, memory, and focus.

10. Sleep Disturbances Changes in sleep patterns, including difficulty falling asleep or staying asleep, are common with hormonal imbalances.

Other Notable Symptoms

11. Hot Flushes Similar to menopause in women, men can experience sudden feelings of warmth and sweating.

12. Decreased Bone Density Long-term low testosterone can lead to osteoporosis and increased fracture risk.

What Causes Low Testosterone in Men Over 40?

Understanding the root causes can help in both prevention and treatment:

Age-Related Decline: Natural ageing is the most common cause, with production slowing in the testes and hypothalamus.

Lifestyle Factors:

  • Chronic stress elevating cortisol levels
  • Poor sleep quality and sleep disorders
  • Excessive alcohol consumption
  • Obesity and sedentary lifestyle
  • Poor nutrition and vitamin D deficiency

Medical Conditions:

  • Type 2 diabetes
  • Sleep apnoea
  • Chronic kidney or liver disease
  • Pituitary gland disorders

Medications:

  • Opioid pain medications
  • Certain antidepressants
  • Corticosteroids

When to Seek Professional Help

If you're experiencing multiple symptoms that are affecting your quality of life, it's time to consult with a healthcare professional. At Menova Health, we specialise in comprehensive hormone assessments that go beyond simple blood tests.

Our evaluation process includes:

  • Detailed symptom assessment
  • Comprehensive hormone panel testing
  • Lifestyle and health history review
  • Personalised treatment recommendations

Red flags that require immediate attention:

  • Severe fatigue affecting work or relationships
  • Complete loss of libido
  • Significant mood changes or depression
  • Rapid muscle loss or weight gain

Treatment Options: Reclaiming Your Vitality

Modern hormone restoration therapy offers several effective treatment options:

Testosterone Replacement Therapy (TRT):

  • Topical gels and creams
  • Injectable testosterone
  • Testosterone pellets
  • Patches and nasal gels

Lifestyle Modifications:

  • Structured exercise programmes focusing on resistance training
  • Optimised nutrition plans
  • Stress management techniques
  • Sleep hygiene improvements

Complementary Treatments:

  • Vitamin D and zinc supplementation
  • Weight management programmes
  • Treatment of underlying conditions

The key is finding the right combination that works for your individual needs and lifestyle.

Frequently Asked Questions About Low Testosterone

How common is low testosterone in men over 40?

Low testosterone affects approximately 40% of men over 45, with the prevalence increasing with age. By age 60, nearly 50% of men experience some degree of testosterone deficiency.

Can low testosterone be reversed naturally?

Whilst lifestyle changes like regular exercise, proper nutrition, adequate sleep, and stress management can help optimise testosterone levels, men with clinically low testosterone typically require medical intervention for significant improvement.

How long does testosterone replacement therapy take to work?

Most men begin noticing improvements in energy and mood within 2-4 weeks of starting treatment. Sexual health improvements typically occur within 6-12 weeks, whilst muscle mass and strength gains may take 3-6 months.

Is testosterone replacement therapy safe long-term?

When properly monitored by qualified healthcare professionals, TRT is generally safe for most men. Regular blood tests and health assessments ensure optimal dosing and early detection of any potential side effects.

What's the difference between low testosterone and erectile dysfunction?

Whilst they're related, they're distinct conditions. Low testosterone affects overall hormone levels and can contribute to ED, but ED can also result from blood flow issues, psychological factors, or other medical conditions. Many men have both conditions.

Will insurance cover testosterone testing and treatment?

Coverage varies by provider and policy. At Menova Health, we work with patients to explore all available options and provide transparent pricing for our comprehensive hormone restoration programmes.

How accurate are at-home testosterone tests?

Whilst convenient, at-home tests may not provide the comprehensive hormone panel needed for accurate diagnosis. Professional testing includes multiple markers and proper timing considerations for the most reliable results.

Can low testosterone affect my partner and relationship?

Absolutely. Low testosterone symptoms like decreased libido, mood changes, and fatigue can impact intimacy and relationship dynamics. Many couples find that addressing hormonal health improves their overall relationship satisfaction.

Take Control of Your Health Today

Don't let low testosterone symptoms control your life any longer. If you're experiencing multiple symptoms that are affecting your energy, relationships, or overall quality of life, it's time to take action.

At Menova Health, we understand that every man's journey is unique. Our team of specialised doctors and healthcare professionals has helped thousands of Australian and New Zealand men reclaim their vitality through personalised hormone restoration programmes.

Why Choose Menova Health?

Over 10 years of specialised men's health experience
Comprehensive hormone testing and assessment
Personalised treatment plans tailored to your lifestyle
Ongoing support with dedicated case managers
Discreet telehealth consultations from the comfort of your home
Access to dieticians, psychologists, and nutritionists
24/7 customer support

Ready to Start Your Journey?

Book your FREE consultation today and discover how hormone restoration can transform your life. During your consultation, our experienced doctors will:

  • Review your symptoms and health history
  • Discuss comprehensive testing options
  • Explain personalised treatment approaches
  • Answer all your questions in a judgement-free environment

Conclusion: Your Path to Renewed Vitality

Low testosterone is more than just a natural part of ageing—it's a treatable condition that doesn't have to define your quality of life. The 12 key symptoms we've explored, from persistent fatigue and decreased libido to mood changes and muscle loss, are clear indicators that your body may need hormonal support.

The key takeaways from this guide:

  • Early recognition matters: Identifying symptoms early allows for more effective treatment and better outcomes
  • Professional assessment is crucial: Comprehensive hormone testing provides the foundation for personalised treatment plans
  • Multiple treatment options exist: From lifestyle modifications to testosterone replacement therapy, there are proven solutions available
  • You're not alone: Nearly half of men over 45 experience some degree of testosterone deficiency

Remember, experiencing these symptoms isn't a sign of weakness or something you simply have to "live with."

Modern hormone restoration therapy has helped thousands of men across Australia and New Zealand regain their energy, confidence, and overall wellbeing.The most important step is the first one—acknowledging that these symptoms are impacting your life and seeking professional guidance.

At Menova Health, our specialised team understands the unique challenges men face and provides discreet, comprehensive care tailored to your individual needs.Don't let another year pass feeling less than your best.

Your relationships, career, and personal happiness deserve the investment in your health. With proper diagnosis and treatment, the vitality and confidence you once enjoyed can be restored.Take control of your health journey today—your future self will thank you for it.